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Role of SIRT1 in NAMPT-induced liver gene expression

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NIAID Data Ecosystem2026-03-13 收录
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We tested they hypothesis that hepatocyte SIRT1 mediates transcriptomic changes induced by hepatocyte-specific NAMPT overexpression We overexpressed NAMPT in western diet-fed WT and SIRT1 liver-specific knockout mice for 12wk and subjected liver tissue to high-throughput RNA sequencing

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2022-03-01
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