HUMAN VH1-RELATED DUAL-SPECIFICITY PHOSPHATASE (VHR) having oxidized catalytic cysteine and complexed with 6-(difluoromethyl)pyrimidin-4-ol at two allosteric sites

HUMAN VH1-RELATED DUAL-SPECIFICITY PHOSPHATASE (VHR) having oxidized catalytic cysteine and complexed with 6-(difluoromethyl)pyrimidin-4-ol at two allosteric sites Descriptor: 6-(difluoromethyl)pyrimidin-4-ol, DIMETHYL SULFOXIDE, Dual specificity protein phosphatase 3 Authors: Aleshin, A.E, Wu, J, Lambert, L.J, Cosford, N.D.P, Tautz, L. Deposit date: 2023-07-25 Release date: 2024-08-14 Last modified: 2025-02-26 Method: X-RAY DIFFRACTION (2 Å) Cite: Fragment Screening Identifies Novel Allosteric Binders and Binding Sites in the VHR ( DUSP3 ) Phosphatase. Acs Omega, 10, 2025