cryo-EM structure of TRPM3 ion channel in complex with Gbg in the presence of PIP2, tethered by ALFA-nanobody

cryo-EM structure of TRPM3 ion channel in complex with Gbg in the presence of PIP2, tethered by ALFA-nanobody Descriptor: (3beta,14beta,17beta,25R)-3-[4-methoxy-3-(methoxymethyl)butoxy]spirost-5-en, 1,2-DIACYL-GLYCEROL-3-SN-PHOSPHATE, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... Authors: Zhao, C, MacKinnon, R. Deposit date: 2022-06-19 Release date: 2022-11-02 Last modified: 2025-06-04 Method: ELECTRON MICROSCOPY (3.8 Å) Cite: Structural and functional analyses of a GPCR-inhibited ion channel TRPM3. Neuron, 111, 2023