Loss of MTGR1 broadly skews intestinal cell lineages. Here, we used sc-RNA sequencing to analyze MTGR1-dependent changes in intestinal cell and stem cell populations. Cells from WT and Mtgr1 null duod

NIAID Data Ecosystem00

Single-cell transcriptomics of Smad4fl/fl and Smad4fl/fl;Rosa26-creERT2 (Smad4iko) mice.

单细胞转录组学

肺部细胞图谱

We report a comprehensive cell atlas of the lungs from Smad4fl/fl and Smad4fl/fl;Rosa26-creERT2 (Smad4iko) mice. Overall design: The mouse lung tissue blocks were dissected from Smad4fl/fl and Smad4fl

NIAID Data Ecosystem00

Single nuclei RNAseq analysis of HD mouse model and human brain reveals impaired 1 oligodendrocyte maturation and potential causal regulators. Single nuclei RNAseq analysis of HD mouse model and human brain reveals impaired 1 oligodendrocyte maturation and potential causal regulators

亨廷顿病少突胶质细胞成熟障碍

单细胞转录组学

A challenge in treating Huntington’s disease (HD) is the complexity of affected brain regions and cell types. We carried out a systematic analysis of cell type-specific changes in cortex and striatum

NIAID Data Ecosystem20

Single-Cell Transcriptome Analysis Reveals Differential Signatures of Human Left-Sided and Right-Sided Colon

单细胞转录组学

左右结肠细胞差异

In our study, we obtained paired normal left-sided and right-sided colon mucosa tissues by colonoscopy, and 9,642 individual cells were analyzed by single-cell RNA-seq, which aims to explore the diffe

NIAID Data Ecosystem00

Single-cell cDNA library data for granulosa cells at germinal vesicle and metaphase I stages

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