Parameter estimates, log-likelihood values and selective pressures across codons for <i>P. falciparum</i> glycerol kinase under models of variable ω ratios.

Models were implemented with the codeml algorithm in the PAML package. Under the M2 model, there were >300 codons with ω<1.0 and a posterior probability of >99% (not listed in table). These were subjected to the SLR test for further categorization of the intensity of purifying selection (see text). There were 21 neutral or positively selected sites (ω≥1) with a Bayes Empirical Bayes (BEB) posterior probability of >50%, although none of these were statistically significant at 95%. Under the M8 model, no statistically significant positively selected sites were identified. For M7 and M8, p and q are the shape parameters of the β distribution. ℓ = log-likelihood estimate, κ = transition/transversion ratio, p = BEB posterior probability. Numbering corresponds to the sequence alignment in Figure 3.