Genomics of signalling crosstalk of estrogen receptor alpha in breast cancer cells

ChEBI2008-05-22 更新2026-07-21 收录

癌症分子生物学

激素受体信号通路

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Genomics of signalling crosstalk of estrogen receptor alpha in breast cancer cells

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2008-05-22

Progesterone receptor genomic and transcriptomic effects are shaped by estrogen priming to produce a unique response in breast cancer cells

乳腺癌分子机制

激素受体信号通路

Introduction: Progesterone receptor (PR) is essential for normal breast homeostatic maintenance and is important for dynamic breast remodelling through the menstrual cycle and pregnancy. Furthermore,

NIAID Data Ecosystem60

Cancer Stem Cell Phenotypes in ER + Breast Cancer Models Are Promoted by PELP1/AIB1 Complexes

癌症分子生物学

激素受体信号通路

Trascriptome analysis of mcf7 cell lines were performed MCF-7 PELP1 cells expressing LXSN, WT PELP1, or cytoplasmic (cyto) PELP1 were hormone-starved in modified IMEM containing 5% DCC for 16 hours pr

NIAID Data Ecosystem50

Table_4_The MYH9 Cytoskeletal Protein Is a Novel Corepressor of Androgen Receptors.docx

前列腺癌分子机制

激素受体信号通路

In the progression of castration-resistant prostate cancer (CRPC), the androgen receptor (AR) that serves as a transcription factor becomes the most remarkable molecule. The transcriptional activity o

NIAID Data Ecosystem20

Luminal HER2 negative tumors. Homo sapiens

癌症分子生物学

年轻患者肿瘤突变

Early age patients less than 36 years represent 4% of breast cancer cases and have a higher probability of being BRCA1/2 mutation carriers. There are indications that tumors from young patients are bi

NIAID Data Ecosystem50

Estrogen receptor beta excerts tumorsuppressive effects in prostate cancer through repression of androgen receptor activity

前列腺癌分子机制

激素受体信号通路

We found that ERbeta activated by ligand eithe E2 or LY3201 repressed AR activity and affected downstream genes regulated by AR Overall design: To investigate the mechanisms of action of ERÃ and its

NIAID Data Ecosystem40

Genomics of signalling crosstalk of estrogen receptor alpha in breast cancer cells

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