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P38 alpha map kinase complexed with BMS-640994

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Protein Data Bank Japan2024-02-21 更新2026-03-21 收录
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P38 alpha map kinase complexed with BMS-640994 Descriptor: Mitogen-activated protein kinase 14, N-[2-methyl-5-(methylcarbamoyl)phenyl]-2-{[(1R)-1-methylpropyl]amino}-1,3-thiazole-5-carboxamide Authors: Sack, J.S. Deposit date: 2008-01-11 Release date: 2008-04-15 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (2.4 Å) Cite: The discovery of (R)-2-(sec-butylamino)-N-(2-methyl-5-(methylcarbamoyl)phenyl) thiazole-5-carboxamide (BMS-640994)-A potent and efficacious p38alpha MAP kinase inhibitor Bioorg.Med.Chem.Lett., 18, 2008

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2008-01-11
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