Background Considerable progress has been made in the HCV evolutionary analysis, since the software BEAST was released. However, prior information, especially the prior evolutionary rate, which plays
Hepatitis C virus (HCV) replication in infected patients produces large and diverse viral populations, which give rise to drug resistant and immune escape variants. Here we analyzed HCV populations du
All HCV levels were normalized to internal control. Internal control was detectable for all samples. Measures of HCV clearance were: k (rate constant) and t1/2 (half-life). (a) r2 was determined from