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Detection of transcriptome changes caused by knockdown of Ptbp1 in U251 GBM cells

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NIAID Data Ecosystem2026-03-13 收录
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We demonstrated that knocking down Ptbp1 can reprogram GBM cells into neuron-like cells. In order to further explore the mechanism of Ptbp1 causing this phenomenon, we performed mRNA sequencing on U251 cells infected with sh-Luci-3d, sh-Ptbp1-3d and sh-Ptbp1-7d. Overall design: The mRNA changes of U251 cells infected with sh-Luci-3d, sh-Ptbp1-3d and sh-Ptbp1-7d were detected.

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2022-06-25
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