Characteristics of colorectal cancer controls by levels of leukocyte genomic DNA methylation in a case-control study nested within the Nurses’ Health Study.

aRegular aspirin use was defined as intake of at least two 325-mg tablets per week in the NHS. bThe body mass index is weight in kilograms divided by the square of the height in meters. cMET denotes metabolic equivalent. Met -hours = sum of the average time/wk in each activity x MET value of each activity. One MET, the energy spent sitting quietly, is equal to 3.5 ml of oxygen uptake per kilograms of body weight per minute for a 70-kg adult. dNutrient values (calcium, folate, and vitamin D) represent the mean of energy-adjusted intakes.