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Crystal structure of the human METTL3-METTL14 complex with compound UOZ016

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Protein Data Bank Japan2024-10-23 更新2026-04-19 收录
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Crystal structure of the human METTL3-METTL14 complex with compound UOZ016 Descriptor: (R)-N-((1-(6-(benzylamino)pyrimidin-4-yl)-3-hydroxypiperidin-3-yl)methyl)-4-((4,4-dimethylpiperidin-1-yl)methyl)benzamide, ACETATE ION, N6-adenosine-methyltransferase catalytic subunit, ... Authors: Bedi, R.K, Huang, D, Caflisch, A. Deposit date: 2021-02-11 Release date: 2021-10-20 Last modified: 2024-10-23 Method: X-RAY DIFFRACTION (1.91 Å) Cite: Structure-Based Design of Inhibitors of the m6A-RNA Writer Enzyme METTL3 Acs Bio Med Chem Au, 2023

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2021-02-11
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