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Reconstructing the three-dimensional architecture of extrachromosomal DNA with ec3D

Figshare2026-01-24 更新2026-04-28 收录

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https://figshare.com/articles/dataset/Reconstructing_the_three-dimensional_architecture_of_extrachromosomal_DNA_with_ec3D/30629882 数据链接链接失效反馈

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资源简介：

Hi-C data of the ecDNA cell line MSTO-211H used by ec3D

应用场景：

创建时间：

2026-01-24

水稻胁迫响应

三维基因组学

Background: The three-dimensional spatial organization of the genome plays important roles in chromatin accessibility and gene expression in multiple biological process, and has been reported to be al

NIAID Data Ecosystem90

Regulation of 3D genome organization, transcription and histone H3K9me2 by histone H3K9 methyltransferases [ChIP-Seq]

表观遗传调控

三维基因组学

Histone H3 lysine 9 dimethylation (H3K9me2) is a highly conserved silencing epigenetic mark. Chromatin marked with H3K9me2 forms large domains in mammalian cells and overlaps well with lamina-associat

NIAID Data Ecosystem80

3D genome landscaping of in vitro totipotent cellular models [Hi-C]

三维基因组学

细胞全能性

Totipotent embryos lack higher-order genome architecture. In this study, we profile the 3D genome architecture of two putative totipotent cellular models, ciTotiSCs and TBLCs. Notably, both ciTotiSCs

NIAID Data Ecosystem40

Additional file 3 of SMOOTH-seq: single-cell genome sequencing of human cells on a third-generation sequencing platform

单细胞基因组学

染色体外DNA

Additional file 3: Table S2. Describes ecDNAs in K562 cells.

NIAID Data Ecosystem90

Whole-genome sequencing analysis of extrachromosomal DNA with Amplicon Architect

胶质母细胞瘤遗传异质性

染色体外DNA

The study is related to our manuscript entitled "Single-cell genetic heterogeneity linked to immune infiltration in glioblastoma". Using multiplexed FISH analysis of 3-4 tumor cores from 17 glioblasto

NIAID Data Ecosystem50

Reconstructing the three-dimensional architecture of extrachromosomal DNA with ec3D

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