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Fluorination of 2<i>H</i>‑Indazoles Using <i>N</i>‑Fluorobenzenesulfonimide

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NIAID Data Ecosystem2026-03-12 收录
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An efficient, simple, and metal-free fluorination of 2H-indazoles has been developed using N-fluorobenzenesulfonimide (NFSI) in water under ambient air. This transformation provides direct access to fluorinated indazole derivatives with broad functionalities in satisfactory yields. The experimental results suggest a radical mechanistic pathway of this protocol.

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2021-07-26
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