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Tcf1/Lef1 transcription factors and CD8 T cell identity [Hi-C]. Tcf1/Lef1 transcription factors and CD8 T cell identity [Hi-C]

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NIAID Data Ecosystem2026-03-12 收录
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Comparison of global genome organization between WT and Tcf1/Lef1-deficient naïve CD8+ T cells Overall design: Splenocytes were harvested from hCD2-Cre, Rosa26-lsl-GFP, Tcf1/Lef1 wild-type or double floxed mice, and sorted for GFP+TCRbeta+ naïve CD8+ T cells, followed by crosslinking, enzyme digestion, proximity ligation, and then HiC sequencing.

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2021-01-12
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