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Identification of a HTT-specific binding motif in DNAJB1 essential for suppression and disaggregation of HTT

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NIAID Data Ecosystem2026-03-14 收录
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Identification of the binding interface between HttExon1Q48 and the molecular chaperone DNAJB1. The proteins were incubated and cross-linked in vitro and the binding interface was mapped to the hinge region between CTDI and CTDII of DNAJB1 and the proline rich domain of HTTEXon1Q48.

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2022-10-15
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