ß-glucan enhances LPS-induced acute lung injury via interferon ?-mediated alveolar macrophages reprogramming

Alveolar macrophages (AMs) are pivotal in maintaining lung homeostasis and orchestrating responses to infections. While traditionally perceived as fixed tissue-resident macrophages (TRM) with limited plasticity, a mounting body of evidence underscores their remarkable capacity to dynamically adjust in the face of varying environmental exposures