Immune responses against influenza infection are mediated by influenza specific antibodies (measured as HI titres), while increasing evidence points to an important role of T cell (CD4; T helper cells
T cell factor 1 (Tcf1, encoded by Tcf7) promotes the central memory CD8+ T cell (TCM) differentiation and homeostatic proliferation in lymphoid tissues. It remains unclear if and how Tcf1 regulates th
Mice were vaccinated with AP205 bacteriophage based VLP vector-plaform or PBS. Transcriptomes of dendritic cells 6 hours after vaccination were used to build a model predictive of the vector-platform
Using the Collaborative Cross, a population of recombinant inbred mouse strains with high levels of genetic variation, we measured antibody response and weight change after infection with influenza-A