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The traits elf18<sup><i>DC</i></sup>- and elf18<sup><i>Ps</i></sup>-induced SGI map a significant number of <i>a priori</i> candidate genes.

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NIAID Data Ecosystem2026-03-09 收录
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We assembled a list of 77 genes that have published evidence to alter SGI in response to either elf18 or flg22. The measure ‘frequency’ indicates how many a priori candidate genes were found among the number of GWA candidate genes (nb. genes) for all peaks of each trait. The empirical p-value is generated by shifting the number of peaks along the genetic positions and calculating the frequency of found a priori genes in the number of genes under these shifted peaks. The random shift along the genetic position maintains patterns of linkage disequilibrium and was repeated 100 times.

我们构建了包含77个基因的列表,这些基因已有公开研究证据表明,其可在响应elf18或flg22时改变SGI。其中“频率(frequency)”这一指标,指的是各性状所有关联峰对应的全基因组关联分析(Genome-Wide Association, GWA)候选基因的数量(即基因数,缩写为nb. genes)中,被检出的先验候选基因(a priori candidate genes)的数量。经验p值(empirical p-value)通过以下方式生成:沿基因组位置对各关联峰进行随机偏移,随后计算这些偏移后的峰所覆盖的基因集合中,检出的先验候选基因的频率。该基因组位置上的随机偏移过程会保留连锁不平衡(linkage disequilibrium)的模式,且该流程被重复执行100次。

创建时间:
2016-06-24
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