In the Metazoan germline, piwi proteins and associated piwi-interacting RNAs (piRNAs) provide a defense system against the expression of transposable elements. In the cytoplasm, piRNA sequences guide
This project sought to conduct an in-depth analysis of the small RNA pathways in whitefly Bemisia tabaci (AZ-B biotype). Based on the characterization of the small RNAs, the project focuses on exploit
Biomolecular condensates are thought to compartmentalize biochemical activities, yet how they control macromolecular access without membranes remains unclear. We show that C. elegans germline condensa
The ubiquitin-proteolytic system controls the stability of proteins in space and time. In this study, using a temperature-sensitive mutant allele of the cul-2 gene, we show that CRL2LRR-1 (CUL-2 RING