A Bench-Stable, Single-Component Precatalyst for Silyl–Heck Reactions

Studies of the silyl-Heck reaction aimed at identifying active palladium complexes have revealed a new species that is formed in situ. This complex has been identified as the palladium iodide dimer, [(JessePhos)­PdI2]2, which has been found to be a competent single-component precatalyst for the silyl-Heck reaction. This complex is easily prepared and is temperature, moisture, and air stable. Additionally, this precatalyst provides higher activity and greater reproducibility compared to previous systems.针对硅基Heck偶联反应（silyl-Heck reaction）中活性钯配合物的鉴定研究，发现了一种原位生成的新型物种。该物种经鉴定为碘化钯二聚体[(JessePhos)­PdI₂]₂，现已证实其可作为硅基Heck偶联反应的单组分活性预催化剂。该配合物制备简便，且对温度、水分与空气均具有良好稳定性。此外，相较于此前的催化体系，该预催化剂展现出更高的催化活性与更优异的重现性。