Composition of developing thrombi obtained from vertical stacks of images collected by multiphoton microscopy of laser induced injuries in mesenteric veins of a mice.

3D image reconstruction of a late stage thrombus is shown in (a) (luminal view) and (b) cross section in a vertical plane (wall is on the left, lumen is on the right). Regions composed mostly of platelets are red, mostly of fibrin - green, composed of platelets and fibrin -yellow; and regions excluding plasma, fibrin and platelets (other material, cells) - black. (c) Shows evolution of the thrombus composition as it stabilizes. Stabilization is associated with decreasing amounts of platelets and increasing amounts of fibrin on the surface.图(a)展示了晚期血栓的三维图像重建结果（管腔视角），图(b)为垂直平面下的横截面视图（血管壁位于左侧，管腔位于右侧）。其中，以血小板为主要构成成分的区域标记为红色，以纤维蛋白为主要构成成分的区域标记为绿色，同时包含血小板与纤维蛋白的区域标记为黄色；不含血浆、纤维蛋白及血小板的区域（其他物质、细胞）则标记为黑色。图(c)展示了血栓稳定过程中的成分演变规律：血栓稳定时，其表面的血小板含量逐渐减少，纤维蛋白含量则逐渐升高。